Early Successes – Adult Stem Cells
- Human mesenchymal stem cells turned on genes found
in bone, cartilage, adipose, muscle, hematopoiesis-supporting
stromal, endothelial, and neuronal cells.
- Multipotent adult progenitor cells have been shown
to differentiate into functional, hepatocyte-like cells.
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Slide 16 of 63
Adult stem cells have shown
great promise in many published studies. These cells have shown the
potential to form many different kinds of cell types and tissues,
including functional hepatocyte-like (liver) cells. Such cells might be
useful in repairing organs ravaged by diseases.
Tremain, N., et al., “MicroSAGE Analysis
of 2,353 Expressed Genes in a Single-Cell Derived Colony of
Undifferentiated Human Mesenchymal Stem Cells Reveals mRNAs of Multiple
Cell Lineages,” Stem Cells 19: 408-418 (2001).
Schwartz, R. E., et al., “Multipotent
adult progenitor cells from bone marrow differentiate into functional
hepatocyte-like cells,” Journal of Clinical Investigation 109:
Last Modified July 6, 2004